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Exam Cram
Exam Cram
Thrombophilias means 'loves to clot' & these are disorders with high rates of thrombosis
Factor V Leiden is the commonest thrombophilia
Thrombophilias are rare but important causes of venous clots (DVT, PE) & arterial clots (strokes, myocardial infarction)
Testing for factor V Leiden is controversial due to its high asymptomatic rates
Thrombophilia screen
Thrombophilia screen
Diseases (7)
Diseases (7)
Protein C deficiency
Protein S deficiency
Antithrombin deficiency (previously thrombin III)
Factor V Leiden (controversial)
Prothrombin gene mutation
Antiphospholipid syndrome (APS): anti B2 glycoprotein-1, anti-cardiolipin
Thrombus disease Overview
Thrombus disease Overview
Arterial
Renal vein thrombosis
Indications for thrombophilia
Indications for thrombophilia
Unusual features:
Young, distribution, recurrance in:
As standard:
Resources and References
Resources and References
Links
Specialties: Haematology, Stroke
References
https://www.southtees.nhs.uk/services/pathology/tests/thrombophilia-screen/
https://www.nbt.nhs.uk/severn-pathology/requesting/test-information/thrombophilia-screen
Written in 2025
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