Anti-Arrhythmic Drugs

Class

1a- quinidine

1b

1c- flecainide

2

3- amiodarone, sotalol

Maintaining AF

Amiodarone is superior to sotalol

Digoxin

• Moa: blocks the Na-H+ pump

Prolongs the cardiac depolarisation

• Indications: atrial fibrillation, no longer used in congestive heart failure

• Toxicity: anxiety, yellow colour vision, bradycardia

• Renally excreted: half life- 36hrs

• Bioavailability 60%

• Measure levels after 6hrs

Indications

Contraindications

Cautions

Side effects