Hyperparathyroidism

Summary

Primary hyperparathyroidism

• Commonest cause of hypercalcaemia

• Terminal phalanx resorption

• Investigations: high PTH, hypercalcaemia, low phosphate, 

• Mx: parathyroidectomy or cinacelet

Secondary hyperparathryoidism

• Occurs in CKD, kidneys fail to respond to parathyroid

• Investigations: high PTH, low calcium, high phosphate, high creatinine

• Mx: po calcium or 1-alpha calcidol, phosphate binders

Tertiary hyperparathyroidism

• Occurs after long term secondary hyperparathyroidism; 

• Where a parathyroid adenoma develops from continued stimulation

• Investigations: high PTH, high calcium, high phosphate, high creatinine, high alk P

• Mx: parathyroidectomy or cinacalet

Resources and References

Page written in 2024.