Complement Disorders

Exam Cram

• Complement C5-9 deficiencies associated with gram -ve bacterial infections

• C1q deficiency associated with Systemic Lupus Erythematous 

• C1 esterase deficiency present in Hereditary Angiodema 

• C4 low in Systemic Lupus Erythematous , T1DM, Cryoglobulinaemia

• C2, C3 & C4 low in Rheumatoid Arthritis 

• C2 deficiency associated bacterial infections

Produced 2024