Huntington's Disease (HD)

Exam Cram

• Huntington's disease also called Huntington's chorea

• Inheritance: autosomal dominant

• CAG repeats: normal 9-35, disease > 36, get longer and present earlier with each generation

• Presentation: chorea (abnormal movements), personality changes, memory loss

• Prognosis: death c. 15yrs after diagnosis c.35yrs

Written 2024