Malaria

Exam Cram

• Malaria is a significant cause of global mortality & morbidity

• Presentation: fever in foreign travel

• Investigations: blood films x3, anaemia, thrombocytopenia, hypoglycaemia

• Management (severe): IV Artesunate

Outline

Management

Non falciparum (Vivax, Ovale)

1. Artemether & lumefantrine + primaquine (treat liver parasites)

2. Chloroquine

Falciparum

Uncomplicated

1. Doxycycline + quinine

Severe

1. Artesunate IV

   1. Step down to artemether- lumefantrine

2. Quinine IV

Markers of Severity

Severe: for IV Artesunate

• GCS < 15

• Hypotension

• Anaemia

• Hypoglycaemia

• Parasitaemia > 10%

References and Resources

Written 2024