BRCA1 & BRCA2

Exam Cram

• BRCA1 & BRCA2 moa: DNA repair, tumour suppression gene

• BRCA 1 & 2 implicated in increased risks of breast & ovarian cancer

BRCA1

Increased risk of:

• Breast cancer

• Ovarian cancer

• Pancreatic cancer

BRCA2

Increased risk of:

• Breast cancer

• Ovarian cancer

• Pancreatic cancer (x22)

• Prostate cancer (x5)

Resources and References

Created in 2024.