Rheumatology

Introduction

Structure

• Physiology

• Pathology

• Clinical 

• Wider

Physiology

Pathology

Arthropathy

Infection

• Septic Arthritis 

• Osteomyelitis 

Crystallopathy

• Gout 

• Pseudogout 

Inflammatory

• Sero positive

  • Rheumatoid Arthritis 

  • Systemic Lupus Erythematous , Systemic Sclerosis , Sjogren's Syndrome 

• Sero negative

  • PEAR: Psoriasis, Crohn's Disease, Ulcerative Colitis, Ankylosing Spondylitis, Reactive Arthritis 

  • Juvenile Idiopathic Arthritis 

Degenerative

• Osteoarthritis

Systemic

Vasculitis

• Large vessel: GCA/ PMR, TA (Takayasu's Arteritis) 

• Medium vessel: Polyarteritis Nodosa (PAN), Kawasaki's Disease

• Small vessel

  • ANCA positive: EGPA, GPA, MPA, 

  • ANCA negative: HSP,

• Rarer

  • Behcet's Disease 

  • Thromboangiitis obliterans (TAO, Buerger's Disease)

  • Cryoglobulinemia 

Connective tissue disorders: 

• Marfan's Syndrome 

• Ehlers Danlos syndrome (EDS)  

Myopathies

• Rhabdomyolysis 

• Muscular dystrophy- Duchenne's, Becker's 

• Dermato/polymyositis 

• Cardiomyopathies

• Osteomalacia, Sarcopenia

Resources and References

Written 2025