Bleeding can present as a medical emergency, typically a variceal upper GI bleed
If severe- senior support, HDU/ ICU setting and A-E initially performed
Aim to blood with blood, consider massive transfusion protocol and reversal agents
Consider underlying cause, e.g. malignancy or haemophilia
Sources of blood loss (head to toe):
Haematoma - intracranial or elsewhere
Epistaxis, bleeding gums
Hematemesis and hematochezia (blood in stool)
Skin lacerations
Long bone fractures
Factors
Trauma/ Atraumatic
Coagulopathy
Congenital Haemophilias
Acquired- thrombocytopenia ,coagulopathies
Iatrogenic- anticoagulants, antiplatelets etc
Operations, procedures
Core Conditions
Upper GI Bleed, Lower GI bleed
Haemorrhagic stroke, subdural/ epidural haematoma
Urological cancer- bladder, renal
Trauma, operations & PPH
Haemophilia, Von WilleBrand Disease
DIC, TTP, HUS, HIT
Osteoporosis
Acute
Stabilise:
Manage in appropriate setting, e.g. HDU
A-E assessment,
Escalate, ask for help, consider peri-arrest buzzer
Consider 0 negative blood, reversal agents and massive transfusion protocol
Consider IVF
Assess underlying cause
Malignancy screen
Haemophilia screen
Assess antiplatelets and anticoagulants
Written in 2025