Acromegaly

Exam Cram

• Pathophysiology: excess growth hormone, usually caused by pituitary adenoma

• Presentation: macroglossia, headaches, joint pains, sweating, HTN, hyperglycaemia

• Investigations: IGF-1 levels

• Management: octreotide

Med Reg Notes

Growth hormone released in pulsatile manner

IGF-1 used to measure tumour re-occurrence

Diagnosis

1. IGF-1 level

2. Growth Hormone levels after glucose tolerance test 

3. MRI Pituitary

Resources and References

Page written in 2024.