Chest pain can be caused by cardiovascular, respiratory, gastro intestinal, musculoskeletal or vascular body systems
Chest pain is most commonly caused by reflux or musculoskeletal sources
Chest pain red flag differentials include: acute coronary syndrome, pericarditis, aortic dissection, pulmonary embolism, pneumothorax, pneumonia, and oesophageal rupture
Chest pain red flag features include: hyperacute onset < 1 minute, hypotension, severe hypoxia
Cardiac ischaemia: central dull ache radiating down left arm/ jaw, autonomic - nausea, sweaty, lightheaded
Pleuritic- worse with breathing suggests respiratory- pulmonary embolism, pneumonia, pneumothorax; or rib fracture/ musculoskeletal or pericarditis
ECG- all patients require ECG ?ACS ?pericarditis
Troponin- low threshold ?ACS
Chest XR- low threshold ?PE, ?pneumothorax ?pneumonia, ?oesphageal rupture
FBC, EUC- ?ACS from T2MI
D-dimer ? PE (often can send coagulation studies and add on D-dimer)
Consider proBNP, ECHO if signs of heart failure
Stabilise via A-E
Treat underlying cause
Symptomatic relief
Paracetamol
Opioids- if severe
NSAIDs- contraindicated in ACS
GTN- reasonable in ACS however contraindicated in right heart failure
Chest pain differentials can be divided into pathologies with findings on investigations (hard chest pain) in the acute setting and those that do not (soft chest pain). Pneumonia is a surprisingly common differential.
Hard chest pain:
NSTEMI, STEMI, unstable angina
Pulmonary embolus
Pneumonia
Pneumothorax
Pericarditis
Aortic dissection
Esophageal rupture
'Soft' chest pain
Angina
Reflux
Musculoskeletal injuries: rib fracture, costochondritis, pulled muscle
Idiopathic- chest wall syndrome
Chest pain work up in the emergency department involves ruling out the 'hard' chest pains and unless concerning angina/ unstable angina, discharging home
Management is largely dictated by the pathology causing the chest pain. See each individual page, below is a summary.
I have been surprised at how many chest pain presentations have been pneumonia.
> chest pain worse with inspiration with purulent sputum +/- fevers, malaise, nausea, reduced PO intake
> focal crepitations on auscultation of lung
> observations: oxygen requirement, tachypnoea, tachycardiac; hypotensive late sign of septic shock from chest sepsis
> CXR shows consolidation in 50-70%, hence a normal CXR does not exclude pneumonia; CRP/ WCC rise show an inflammatory response
> Management: CURB score 0-1- discharge with PO antibiotics e.g. amox 500mg TDS 5d; higher severity score -> IV antibiotics: IV amoxicillin 1g TDS +/- clarithromycin for atypicals and 2L of IVF, admit to general medicine/ respiratory
Pulmonary embolus
Pneumothorax
Aortic Dissection
Oesphageal rupture
ECG
Troponin
CXR
D-dimer
Lactate
Full set of bloods
proBNP
72hr ECG
ECHO
Summary
Soft chest pain is defined by myself as chest pain with normal investigations. The cause includes:
Musculoskeletal chest pain
Coronary artery disease: angina or unstable angina
GI: reflux, gastritis, oesphagitis
Idiopathic
Musculoskeletal
CAD
Exercise tolerance test or stress echo
Chest pain
Settings: GP, A&E, medical assessment unit & inpatient
History
Examination
Observations
Investigations
Differentials
Heart
Coronary artery disease: angina -> unstable angina -> NSTEMI -> STEMI
Lungs
Pneumonia
Pneumothorax
Pulmonary embolus
Vascular: Aortic dissection
Musculoskeletal
Rib #
Intercostal muscle sprain
Management
This presentation is managed largely with information within the history but also with a few key investigations.
Setting
The setting provides context to the pain and the patient's perception of its severity. Medicine often boils down to probabilities and the rates of myocardial infarction are different in a cohort presenting with chest pain to the GP vs to A&E vs to medical assessment unit vs as an inpatient. Some GP practices as part of their phone service will state all chest pains require assessment at hospital. As someone working in hospital I can both understand the difficulty of assessing chest pain without an ECG or troponin (there are sometimes surprises), on the other hand it would feel sensible to take a quick history to ensure the patient truly has chest pain before sending them to hospital (rather than simple reflux, for example.
On the other hand if an individual is happy to wait in A&E for four hours then they likely feel the pain is significant enough to justify this expense. Surgeons will have a low threshold for asking for medical input for a chest pain, a common scenario is a type II MI secondary to biliary sepsis or an NSTEMI presenting with ?biliary colic.
Assessing chest pain at the GP
A history should be taken and if true chest pain this is normally assessed at the hospital
Indications for referral into hospital:
?acute stemi 999 ambulance to A&E, preferably hospital with primary PCI
?Nstemi, unstable angina Medics/ A&E
?Pneumothorax Medics /A&E
?Pulmonary embolus Medics
History
Pleurisy is pain with breathing in, this is caused by a rib#, muscle damage, pneumothorax, pulmonary embolus and pneumonia.
Examination
This is usually unhelpful however a focused examination is integral to a thorough assessment.
Full A-E
B- auscultate, RR, sats,
C- auscultate HS, pulse regular, WWP? (warm and well perfused)
D- GCS, temp, BM
E- abdo + calf ?tenderness, any markings on chest wall ?bruise
Extra Tips:
Palpate the area that is painful
Palpating the area that is painful can suggest a musculoskeletal problem or rib #.
Investigations
Personally I believe all chest pains require an ecg, full set of bloods (FBC, UEs, CRP +/- LFTs) with a troponin and chest x-ray as standard (differing views exist!).
Management
Symptom control
Therapeutic
Chest pain symptom control follows core principles for pain management. See Analgesia for further information.