Latent Autoimmune Diabetes in Adults (LADA)

Exam Cram

• LADA = similar to type 1 diabetes, latent onset (presents in adults)

Outline

Background 

Diagnosis

• Raised HbA1c, polyuria/ polydipsia

• Urinary ketones shows hypoinsulinaemia (insulinopaenia)

• Older, slower progression

Differentials

• MODY and T2DM won't have ketones 

• T1DM has a younger more acute presentation

History:

Examination:

Ix

• anti GAD positive

Management

Can be managed on gliclazide

Ketonuria -> insulin

Deeper Dive

References