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Exam Cram
Exam Cram
Varizella zoster virus (VZV) = Herpes simplex virus 3 causes Chickenpox with first infection and Shingles with reinfection
Chickenpox: body rash with small itchy vesicles and kolpik spots- mouth ulcers
VZV sits in dorsal root ganglion and reactivates to form shingles when old/ immunocompromised
Shingles pc: painful vesicles within a unilateral dermatome distribution
Chicken Pox
Chicken Pox
Background
Background
Diagnosis
Diagnosis
Diagnostic criteria:
History:
Examination:
Ix
Differentials
Management
Management
Pregnancy or Immunocompromised PEP (Post exposure Prophylaxis)
Pregnancy or Immunocompromised PEP (Post exposure Prophylaxis)
Post exposure prophylaxis
Management
If contact < 10 days test VZV IgG: for immunity
If nil IgG give IVIG VZV
PO Aciclovir if signs of chickenpox (ideally within 24hrs of rash)
IV Aciclovir if signs of VZV pneumonitis
VZV vaccine can be considered, however will not affect acute mx of post exposure prophylaxis. If IgG VZV +ve, nil action required- shows immune.
Shingles
Diagnosis
Diagnosis
Diagnostic criteria:
History:
Back/ flank pain- 48hrs prior to vesicles
Examination:
Ix
Differentials
Management
Management
Supportive
IV aciclovir
?dex
Post herpatic neuralgia- ?carbamazepine, gabapentinoids/ amitriptyline
References
References
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