Cardiovascular System

Furosemide leads to reduction in pre-load

Betablockers reduce after load

Preload- initial stretching of heart and maximum diastole

After load is particularly the peripheral arterial resistance the heart must pump against

Venodilators reduce pre load (nitrates)

Arterial dilators reduced after load (hydralazine)

BNP- lows BP, preload

• reduces renin and aldosterone activity

• increases salt and water excretion