Newborn Blood Spot 

Indications

Offered to all newborn babies in the UK when 5 days old

Tests for 9 conditions

• Cystic Fibrosis 

• Sickle Cell Disease 

• Congenital HypoThyroidism 

• Homocystinuria (HCU)

• 4 more metabolic conditions

  • Phenylketonuria (PKU)

  • Maple Syrup Urine Disease (MSUD)

  • Isovaleric Acidaemia (IVA)

  • Glutaric Aciduria type 1 (GA1)

Resources and References

1. https://www.nhs.uk/conditions/baby/newborn-screening/blood-spot-test/

Written in 2025